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The Alzheimer's Library
Alzheimer\'s and Inhaled Insulin

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Glucose intolerance, insulin resistance, and pathological features of alzheimer ...

Votes:14 Comments:0
IMPORTANCE: Peripheral glucose homeostasis has been implicated in the pathogenesis of Alzheimer disease (AD). The relationship among diabetes mellitus, insulin, and AD is an important area of investi READ MORE
http://news.medlive.cn/uploadfile/20130805/13756829406221.pdf

Intranasal treatment of central nervous system dysfunction in humans

Votes:39 Comments:0
One of the most challenging problems facing modern medicine is how to deliver a given drug to a specific target at the exclusion of other regions. For example, a variety of compounds have beneficial e READ MORE
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761088/

Sex and ApoE genotype differences in treatment response to two doses of intranas...

Votes:25 Comments:0
A previous clinical trial demonstrated that four months of treatment with intranasal insulin improves cognition and function for patients with Alzheimer's disease (AD) or mild cognitive impairment (MC READ MORE
http://www.ncbi.nlm.nih.gov/pubmed/23507773

First clinical data of the neuroprotective effects of nasal insulin application ...

Votes:12 Comments:0
Previous reviews have outlined the important role of insulin in the brain, and the observation that insulin signaling is desensitized in patients with Alzheimer's disease (AD). Because insulin is used READ MORE
http://www.alzheimersanddementia.com/article/S1552-5260%2813%2902920-8...

Intranasal insulin as a treatment for Alzheimer's disease: a review of basic res...

Votes:4 Comments:0
Research in animals and humans has associated Alzheimer’s disease (AD) with decreased cerebrospinal fluid levels of insulin in combination with decreased insulin sensitivity (insulin resistance) in th READ MORE
http://europepmc.org/articles/PMC3709085

Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Imp...

Votes:33 Comments:0
Objective: To examine the effects of intranasal insulin administration on cognition, function, cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild cognitive i READ MORE
http://archneur.jamanetwork.com/article.aspx...

Inhaled Insulin for Alzheimer's Disease: Phase II Clinical Trial Results -- Over...

Votes:19 Comments:0
The recent results from a clinical trial of insulin for the treatment of AD has garnered a great deal of media attention. Before discussing the research, it is worth reviewing insulin's role in the br READ MORE
http://blog.alz.org/inhaled-insulin-for-alzheimer%E2%80%99s-disease-ph...
Alzheimer's and diabetes have much in common, including many risk factors and underlying pathological mechanisms. It stands to reason that treatments which might be helpful for diabetics might also be helpful for Alzheimer's patients.
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