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The Alzheimer's Library
Glutamate Blockers for Treating Alzheimer\'s

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Efficacy of memantine for agitation in Alzheimer's dementia: a randomized double...

Votes:30 Comments:0
Namenda is known in Europe as Ebixa and generically as memantine. It is typically prescribed for mid-stage Alzheimer's disease. According to a new study conducted by researchers from the U.K., U.S. READ MORE
http://alzheimersweekly.com/content/namendas-benefits-and-failings

Efficacy of memantine for agitation in Alzheimer's dementia: a randomized double...

Votes:16 Comments:0
Background Agitation in Alzheimer's disease (AD) is common and associated with poor patient life-quality and carer distress. The best evidence-based pharmacological treatments are antipsychotics wh READ MORE
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.003...

Meta-analysis of six-month memantine trials in Alzheimer's disease

Votes:13 Comments:0
BACKGROUND: Clinical trials have suggested benefits of memantine for all stages of Alzheimer's disease (AD). A meta-analysis of memantine trials in outpatients with probable AD was conducted. ME READ MORE
http://www.ncbi.nlm.nih.gov/pubmed/19595910

Improvement in behavioural symptoms in patients with moderate to severe Alzheime...

Votes:28 Comments:0
INTRODUCTION: Behavioural disturbances are a common and distressing aspect of Alzheimer's disease (AD). This pooled analysis evaluated the specific benefits of memantine on behavioural disturbances in READ MORE
http://www.ncbi.nlm.nih.gov/pubmed/18058838

Stopping Namenda

Votes:8 Comments:0
Dr. Kevin O'Neil's comment: Memantine is indicated for the treatment of moderate to severe Alzheimer's disease. Several clinical studies have demonstrated in such persons a favorable effect on cogniti READ MORE
http://www.jamda.com/article/S1525-8610%2809%2900522-2/abstract

Clinical experience of memantine in Alzheimer's disease

Votes:24 Comments:0
The true usefulness of any treatment is determined by how the agent performs in everyday clinical practice, how a patient feels and functions subjectively during treatment with the agent and how willi READ MORE
http://www.touchneurology.com/files/article_pdfs/blesa.pdf

Memantine for dementia

Votes:7 Comments:0
Background: Memantine, a low affinity antagonist to glutamate NMDA receptors, may prevent excitatory neurotoxicity in dementia. Objectives: To determine efficacy and safety of memantine for people READ MORE
http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD003154/...

Effectiveness of Cholinesterase Inhibitors and Memantine for Treating Dementia

Votes:15 Comments:0
Background: The effectiveness of the 5 U.S. Food and Drug Administration-approved pharmacologic therapies for dementias in achieving clinically relevant improvements is unclear. Purpose: To review READ MORE
http://www.annals.org/cgi/content/full/148/5/379
Namenda (memantine) is an NMDA receptor agonist, or glutamate blocker, that has been FDA-approved for treating moderate to severe Alzheimer's. There is some anecdotal evidence it may be helpful in treating frontotemporal dementia (FTD).
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