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The Alzheimer's Library
Treatments for Alzheimer\'s Psychiatric Symptoms

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ACNP White Paper: Update on Use of Antipsychotic Drugs in Elderly Persons with D...

Votes:31 Comments:0
In elderly persons, antipsychotic drugs are clinically prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications (schizophrenia and bipola READ MORE
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553721/

Efficacy and Adverse Effects of Atypical Antipsychotics for Dementia: Meta-analy...

Votes:22 Comments:0
Objective: Atypical antipsychotic medications are widely used to treat delusions, aggression, and agitation in people with Alzheimer disease (AD) and other dementia. Several clinical trials have not s READ MORE
http://www.geertswalaszek.com/geropsych/docs/schneider-ajgp-2006.pdf

Effectiveness of Atypical Antipsychotic Drugs in Patients with Alzheimer's Disea...

Votes:27 Comments:0
Delusions, hallucinations, aggression, and agitation affect more than half of patients with Alzheimer's disease and related dementias.1-4 Antipsychotic drugs are used to treat these behaviors and symp READ MORE
http://www.nejm.org/doi/full/10.1056/NEJMoa061240#t=articleBackground

Atypical Antipsychotics May Hasten Cognitive Decline in Alzheimer's

Votes:33 Comments:0
August 18, 2011 -- Use of atypical antipsychotics to treat agitation or psychosis in patients with Alzheimer's disease (AD) may lead to severe cognitive impairment, according to new findings from th READ MORE
http://www.medscape.com/viewarticle/748236

Cognitive Effects of Atypical Antipsychotic Medications in Patients With Alzheim...

Votes:6 Comments:0
Objective: The impact of the atypical antipsychotics olanzapine, quetiapine, and risperidone on cognition in patients with Alzheimer's disease is unclear. The authors assessed the effects of time and READ MORE
http://ajp.psychiatryonline.org/cgi/content/abstract/appi.ajp.2011.081...

Improvement in behavioural symptoms in patients with moderate to severe Alzheime...

Votes:20 Comments:0
INTRODUCTION: Behavioural disturbances are a common and distressing aspect of Alzheimer's disease (AD). This pooled analysis evaluated the specific benefits of memantine on behavioural disturbances in READ MORE
http://www.ncbi.nlm.nih.gov/pubmed/18058838/

Efficacy of treating pain to reduce behavioural disturbances

Votes:23 Comments:0
Objective To determine whether a systematic approach to the treatment of pain can reduce agitation in people with moderate to severe dementia living in nursing homes. Design Cluster randomised cont READ MORE
http://www.bmj.com/content/343/bmj.d4065.full...

Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric sympt...

Votes:4 Comments:0
Context Cholinesterase inhibitors are the primary treatment for the cognitive symptoms of Alzheimer disease (AD). Cholinergic dysfunction is also associated with neuropsychiatric and functional defic READ MORE
http://jama.ama-assn.org/content/289/2/210.full

Extrapyramidal Side Effects in the Psychiatric Emergency Service

Votes:21 Comments:0
The benefits that neuroleptic medications provide in treating psychotic symptomatology in schizophrenia are well established (1). In addition, neuroleptic medications are often used to treat acute, ps READ MORE
http://psychservices.psychiatryonline.org/cgi/content/full/51/3/287

Management of psychosis in patients with Alzheimer's disease: focus on aripipraz...

Votes:34 Comments:0
Psychosis of Alzheimer's disease (AD) is characterized by delusions or hallucinations and may be associated with agitation, negative symptoms or depression. There are no psychotropic medications that READ MORE
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682381/

Antipsychotics for the Treatment of Behavioral and Psychological Symptoms of Dem...

Votes:4 Comments:0
Behavioral and psychological symptoms of dementia (BPSD), i.e. verbal and physical aggression, agitation, psychotic symptoms (hallucinations and delusions), sleep disturbances, oppositional behavior, READ MORE
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647149/

Safety and efficacy of antipsychotic drugs for the behavioral and psychological ...

Votes:39 Comments:0
Background: Antipsychotic drugs are commonly used in the treatment of the behavioral and psychological symptoms of dementia (BPSD). Materials and Methods: We present a qualitative review of the data READ MORE
http://indianjpsychiatry.org/article.asp...

Antipsychotic Drug Use and Mortality in Older Adults with Dementia

Votes:31 Comments:0
Background: Antipsychotic drugs are widely used to manage be- havioral and psychological symptoms in dementia despite concerns about their safety. Objective: To examine the association between trea READ MORE
http://assets0.pubget.com/pdf/17548409.pdf

ACNP White Paper: Update on Use of Antipsychotic Drugs in Elderly Persons with D...

Votes:9 Comments:0
In elderly persons, antipsychotic drugs are clinically prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications (schizophrenia and bipola READ MORE
http://www.nature.com/npp/journal/v33/n5/full/1301492a.html

Adverse Effects of Antipsychotics and Mood Stabilizers

Votes:6 Comments:0
Although psychotropic medications have revolutionized the treatment of many psychiatric disorders, the benefits sometimes come at a price. Unwanted adverse effects may limit the use of these agents an READ MORE
http://www.psychiatrictimes.com/display/article/10168/1147571...

Atypical antipsychotics to treat the neuropsychiatric symptoms of dementia

Votes:7 Comments:0
Neuropsychiatric symptoms are common in older adults with dementia and can be associated with a rapid decline in cognitive and functional status. This article reviews the current literature supporting READ MORE
http://www.pubmedcentral.nih.gov/articlerender.fcgi...

Beyond the Black Box: What is The Role for Antipsychotics in Dementia?

Votes:32 Comments:0
There is a small but well-established increase in the risk of death and stroke when using atypical antipsychotics in older adults with dementia. Clinicians and patients/caregivers are left with a seem READ MORE
http://www.pubmedcentral.nih.gov/articlerender.fcgi...

Pharmacological treatment of neuropsychiatric symptoms of dementia. A review of ...

Votes:23 Comments:0
Context: Neuropsychiatric symptoms of dementia are common and associated with poor outcomes for patients and caregivers. Although nonpharmacological interventions should be the first line of treatmen READ MORE
http://jama.ama-assn.org/cgi/content/full/293/5/596

Psychiatric symptoms of dementia: Treatable, but no silver bullet.

Votes:9 Comments:0
Behavioral problems are common in dementia and may reduce the quality of life of the patient and disrupt the home life of family members. Families want a pill that can cure the myriad phenotypes of a READ MORE
http://www.ccjm.org/content/76/3/167.long

Antipsychotic Medications - Black Box Warning

Votes:28 Comments:0
Antipsychotic Medications - Black Box Warning Increased Chance of Death for Some Elderly Patients Do you have an elderly family member of friend suffering from Alzheimer's, vascular dementia, or a READ MORE
http://bipolar.about.com/od/antipsychotics/a/1blackbox.htm

Medicines for behavioral problems

Votes:22 Comments:0
When Alzheimer's disrupts memory, language, thinking and reasoning, these effects are referred to as "cognitive symptoms" of the disease. The term "behavioral and psychiatric symptoms" describes a lar READ MORE
http://www.alz.org/alzheimers_disease_behavioral_symptoms_ad.asp

Medications for the treatment of behavioral problems associated with dementia

Votes:11 Comments:0
It is my hope that the following discussion on medications will make the care of the patient with dementia more understandable and improve their functional ability. The major types of dementia are tho READ MORE
http://64.26.26.159/abtalz/medsdrsteinke.asp
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