BACKGROUND:
Clinical trials have suggested benefits of memantine for all stages of Alzheimer's disease (AD). A meta-analysis of memantine trials in outpatients with probable AD was conducted.
ME READ MORE http://www.ncbi.nlm.nih.gov/pubmed/19595910
INTRODUCTION: Behavioural disturbances are a common and distressing aspect of Alzheimer's disease (AD). This pooled analysis evaluated the specific benefits of memantine on behavioural disturbances in READ MORE http://www.ncbi.nlm.nih.gov/pubmed/18058838
The true usefulness of any treatment is determined by how the agent performs in everyday clinical practice, how a patient feels and functions subjectively during treatment with the agent and how willi READ MORE http://www.touchneurology.com/files/article_pdfs/blesa.pdf
Background: The effectiveness of the 5 U.S. Food and Drug Administration-approved pharmacologic therapies for dementias in achieving clinically relevant improvements is unclear.
Purpose: To review READ MORE http://www.annals.org/cgi/content/full/148/5/379
Namenda (memantine) is an NMDA receptor agonist, or glutamate blocker, that has been FDA-approved for treating moderate to severe Alzheimer's. There is some anecdotal evidence it may be helpful in treating frontotemporal dementia (FTD).