INTRODUCTION: Behavioural disturbances are a common and distressing aspect of Alzheimer's disease (AD). This pooled analysis evaluated the specific benefits of memantine on behavioural disturbances in READ MORE http://www.ncbi.nlm.nih.gov/pubmed/18058838/
Objective To determine whether a systematic approach to the treatment of pain can reduce agitation in people with moderate to severe dementia living in nursing homes.
Design Cluster randomised cont READ MORE http://www.bmj.com/content/343/bmj.d4065.full...
Atypical antipsychotic drugs have been used off-label in clinical practice for treatment of serious dementia-associated agitation and aggression. Following reports of cerebrovascular adverse events as READ MORE http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674239/
Numerous recent studies have challenged the widely held belief that atypical antipsychotics are safe and effective options for the treatment of behavioural problems such as agitation in patients with READ MORE http://www.ncbi.nlm.nih.gov/pubmed/18447403