Review articles and commentaries about recent developments in Alzheimer's drug development.

Conference on Clinical Trials on Alzheimer's Disease
Almost invariably when Alzheimer's disease is mentioned, be it in the media or in medical reports, the words "for which there is no cure" appear with depressing regularity. The Conference on Clinic
From Therapeutic Advances in Neurological Disorders: Do Amyloid-lowering Strategies Work Clinically?
Nowadays, the amyloid hypothesis, introduced more than 20 years ago, is the most widely accepted hypothesis explaining the development of Alzheimer's disease (AD) [Hardy et al. 1992]. According to thi
Pharmacological Treatment of Alzheimer’s Disease: Is it Progressing Adequately?
Introduction: Between 1993 and 2000 four acetylcholinesterase inhibitors were marketed as a symptomatic treatment for Alzheimer’s disease (AD), as well as memantine in 2003. Current research is focu
Recent advances in dementia research
Recent reports from the 2008 International Conference on Alzheimer's Disease and numerous articles indicate substantial progress in the diagnosis and treatment of Alzheimer's disease. However, the pro
The role of neurogenesis in neurodegenerative diseases and its implications for therapeutic development
Abstract: Neurodegenerative diseases are characterised by a net loss of neurons from specific regions of the central nervous system (CNS). Until recently, research has focused on identifying mechanism