Four cholinesterase inhibitors have been approved by the FDA for treating Alzheimer's. Three of these are often prescribed: Aricept (donepezil), Razadyne (galantamine), and Exelon (rivastigmine). The fourth, Cognex (tacrine) is rarely prescribed nowadays, due to its liver toxicity.

23 mg Aricept: Drug Dosage Was Approved Despite Warning
Four months before a best-selling Alzheimer's drug was set to lose its patent protection, its makers received approval for a higher dosage that extended their exclusive right to sell the drug. But the
Cholinesterase inhibitor effectiveness may be influenced by PON-1 gene
Responsiveness to cholinesterase inhibitors in Alzheimer's disease: a possible role for the 192 Q/R polymorphism of the PON-1 gene. Pola R, Flex A, Ciaburri M, Rovella E, Valiani A, Reali G, Si
Cholinesterase inhibitor efficacy -- brief overview
Medication for Alzheimer's disease Last updated: Tuesday, December 09, 2008 Currently, three drugs are available that can improve memory and delay disease progression in Alzheimer's disease. The d
Cholinesterase inhibitor use in nursing homes
Approximately One-Third of Nursing Home Residents With Dementia Use Cholinesterase Inhibitors: Presented at AAGP By Emma Hitt, PhD HONOLULU -- March 8, 2009 -- Cholinesterase inhibitors are used
Cholinesterase Inhibitors -- Assessing Their Effects
Management of Alzheimer's Disease: Assessing the Effects of Cholinesterase Inhibitors (From: The Canadian Journal of Diagnosis, Vol. 20, No. 6, p. 49-52.) Editorial Consultant Bernard Groulx, M
Cholinesterase inhibitors -- Cochrane database review
SUMMARY Cholinesterase inhibitors (ChEIs), donepezil, galantamine and rivastigmine are efficacious for mild to moderate Alzheimer's disease Alzheimer's disease is the commonest cause of dementia
Cholinesterase inhibitors delay nursing-home placement
Cholinesterase inhibitors may delay nursing-home placement in Alzheimer's There is considerable debate on the value of the cholinesterase inhibitors (donepezil, rivastigmine, galantamine, etc.) in
Cholinesterase Inhibitors for Alzheimer's & Related Dementias CME
The Management of Alzheimer's Disease and Related Dementias: Part 2 -- The Role of Cholinesterase Inhibitors in the Treatment of Alzheimer's Disease and Related Dementias Steven G. Potkin, MD Co
Cholinesterase inhibitors for Alzheimer's disease
Examples Brand Name Chemical Name Aricept donepezil Razadyne galantamine Exelon rivastigmine How It Works Cholinesterase inhibitors in
Cholinesterase inhibitors for managing behavioral problems
Abstract: Alzheimer's disease is characterized by progressive cognitive and functional decline and the emergence of behavioral disturbances. Behavioral symptoms, in particular, cause great distress
Cholinesterase Inhibitors Reduce Aggression, Wandering And Paranoia
10 Dec 2008: Cholinesterase inhibitors, used to treat cognitive symptoms of Alzheimer's disease, are also a safe and effective alternative therapy for the behavioral and psychological symptoms of dem
Criteria for prescribing / using cholinesterase inhibitors
Updated Criteria for Use: Cholinesterase Inhibitors to Treat Dementia VHA Pharmacy Benefits Management Service and the Medical Advisory Panel The following recommendations are based on current m
Do cholinergic therapies have disease-modifying effects in Alzheimer’s disease?
Do cholinergic therapies have disease-modifying effects in Alzheimer’s disease? Marwan N. Sabbagh, Martin R. Farlow, Normal Relkin, Thomas G. Beach The most widely studied and used therapies fo
Do cholinesterase inhibitors modify disease progression
Abstract: Much evidence shows that cholinesterase inhibitor drugs such as Aricept, Exelon and reminyl are clinically effective treatments for people with Alzheimer's disease, and probably also help
Driving Attention Improved With Drugs Used in Alzheimer's Patients
CHICAGO -- July 29, 2008 -- Patients with early Alzheimer's disease who are being treated with an acetylcholinesterase inhibitor have better motor vehicle driving skills compared with those who are no
Effects of donepezil 23 mg on Severe Impairment Battery domains in patients with moderate to severe Alzheimer's disease
The US Food and Drug Administration approved a 23 mg daily dose of donepezil for treatment of moderate to severe Alzheimer's disease (AD) based on outcomes from a large trial comparing the 23 mg/day d
Generic Drugs for Alzheimer's
Alzheimer's Association statement: Switching to generic galantamine In Alzheimer’s disease, as with any medical condition, physicians consider several factors before deciding which medications wil
Long-term use of cholinesterase inhibitors -- 2000 review
Cholinesterase inhibitors stabilize Alzheimer's disease. Giacobini E. University Hospitals of Geneva, Department of Geriatrics, University of Geneva, Medical School, CH-1226 Thonex, Geneva
Long-term use of cholinesterase inhibitors -- 2005 study
Cognitive performance in patients with Alzheimer's disease receiving cholinesterase inhibitors for up to 5 years. Bullock R, Dengiz A. The cholinesterase inhibitors (ChE-Is)--rivastigmine, donep
Long-term use of cholinesterase inhibitors -- 2007 review
Is long-term treatment of Alzheimer's disease with cholinesterase inhibitor therapy justified? Seltzer B. The cholinesterase inhibitors (ChEIs) donepezil, rivastigmine and galantamine are th
Long-term use of cholinesterase inhibitors -- 2008 paper
The effect of cholinesterase inhibitors on decline in multiple functional domains in Alzheimer's disease: a two-year observational study in the Sunnybrook dementia cohort Pearl Behl, Krista L. Lanc
Results from the first long-term study of Alzheimer's drugs
Extended treatment with Alzheimer's disease drugs can significantly slow the rate at which the disorder advances, and combination therapy with two different classes of drugs is even better at helping
Rivastigmine for Alzheimer's disease -- Cochrane Review
Summary: Rivastigmine is beneficial for people with Alzheimer's disease. Alzheimer's disease (AD) is the commonest cause of dementia affecting older people, and is associated with loss of cholinerg
Safety and efficacy of rivastigmine in patients with Alzheimer's disease not responding adequately to donepezil
Objective: Switching patients with Alzheimer's disease from one cholinesterase inhibitor to another represents a viable option for patients not responding to current therapy. The objective of this lar
Treatment effects in multiple cognitive domains in Alzheimer's disease: a two-year cohort study
Introduction Despite widespread use of second-generation cholinesterase inhibitors for the symptomatic treatment of Alzheimer's disease (AD), little is known about the long term effects of choliner
Trio of Drugs May Improve Alzheimer's
Trio of Drugs May Improve Alzheimer's Modest Gains in Mental Skills Seen With Aricept, Razadyne, and Exelon By Miranda Hitti WebMD Health News Reviewed by Louise Chang, MD Jan. 25, 2006 -- For
Watchdog Groups Asks FDA to Withdraw Donepezil 23 Mg
Shortly after patent protection on donepezil (Aricept) expired late in 2009, the manufacturer introduced a new version containing a higher dose, with advertisements claiming it was effective for treat