The pathologies underlying the frontotemporal dementias are many and complex. Some researchers feel these disorders should be separated into at least two different groups.

Frequency of Alzheimer's pathology in progressive focal cortical syndromes
SUMMARY: To determine the frequency of Alzheimer's disease (AD) pathology in patients presenting with progressive focal cortical syndromes, notably posterior cortical atrophy (PCA), corticobasal synd
http://brain.oxfordjournals.org/cgi/content/full/1...
Glucose metabolism in frontotemporal dementia (FTD)
OBJECTIVE: To identify the pattern of progression of decline of cerebral glucose metabolism in frontotemporal dementia (FTD, frontal variant). METHODS: 22 patients with mild FTD underwent 18F-FDG-posi
http://www.ncbi.nlm.nih.gov/pubmed/16448722
Semantic dementia: a unique clinicopathological syndrome
Semantic dementia (SD), one of the main clinical variants of frontotemporal dementia, presents a unique combination of clinical and imaging abnormalities. We describe the epidemiological, cognitive, a
http://www.ncbi.nlm.nih.gov/pubmed/17945154
TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions
ABSTRACT Background: TDP-43 is a major ubiquitinated disease protein in the pathologic condition of frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U). Objective: To
TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degener...
Ubiquitin-positive inclusions in FTD and motor neuron disease
Frontotemporal lobar degeneration (FTLD) with tau-negative, ubiquitin-positive inclusions has been a topic of major interest in recent years, with this group now accounting for the majority of tau-neg
http://www.ncbi.nlm.nih.gov/pubmed/16409556