Alzheimer's and Inhaled Insulin, The Alzheimer's Librar...
Alzheimer's and diabetes have much in common, including many risk factors and underlying pathological mechanisms. It stands to reason that treatments which might be helpful for diabetics might also be helpful for Alzheimer's patients.
Previous reviews have outlined the important role of insulin in the brain, and the observation that insulin signaling is desensitized in patients with Alzheimer's disease (AD). Because insulin is used
First clinical data of the neuroprotective effects of nasal insulin application ...
IMPORTANCE: Peripheral glucose homeostasis has been implicated in the pathogenesis of Alzheimer disease (AD). The relationship among diabetes mellitus, insulin, and AD is an important area of investi
Glucose intolerance, insulin resistance, and pathological features of alzheimer ...
The recent results from a clinical trial of insulin for the treatment of AD has garnered a great deal of media attention. Before discussing the research, it is worth reviewing insulin's role in the br
Inhaled Insulin for Alzheimer's Disease: Phase II Clinical Trial Results --...
Research in animals and humans has associated Alzheimer’s disease (AD) with decreased cerebrospinal fluid levels of insulin in combination with decreased insulin sensitivity (insulin resistance) in th
Intranasal insulin as a treatment for Alzheimer's disease: a review of basi...
Objective: To examine the effects of intranasal insulin administration on cognition, function, cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild cognitive i
Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Imp...
One of the most challenging problems facing modern medicine is how to deliver a given drug to a specific target at the exclusion of other regions. For example, a variety of compounds have beneficial e
A previous clinical trial demonstrated that four months of treatment with intranasal insulin improves cognition and function for patients with Alzheimer's disease (AD) or mild cognitive impairment (MC
Sex and ApoE genotype differences in treatment response to two doses of intranas...
